José O. Ladrönn (born 1967) is a comic book penciller and inker born in Mexico.

Comic book titles he has contributed to include Cable, Spider-Boy Team-Up, Superman Transilvane and Inhumans. In the 2006 he received an Eisner Award (Best Painter/Multimedia Artist) for his work with writer and publisher Richard Starkings on Hip Flask: Mystery City, one of a series of Hip Flask one-shots published by Active Images.

In 2004 he worked with the Chilean author Alejandro Jodorowsky in the story Tears of gold published in the U.S. by Metal Hurlant magazine.

Prior to 2010, he also regularly contributed covers for various titles such as Marvel's Incredible Hulk and DC Comics' Countdown to Infinite Crisis: The OMAC Project.

He is currently working on Hip Flask volume 5 as well The Sons of El Topo with Alejandro Jodorowsky.

Interior comic work includes:

• Cable #-1, 48-70 (with James Robinson and Joe Casey, Marvel Comics, 1997–1999)
• Final Incal (with Alejandro Jodorowsky, Humanoids Publishing, 2014)
• Sons of El Topo - "Les Fils d'El Topo - Tome 1 - Caïn" (with Alejandro Jodorowsky, 2016)
• Thor Annual 2000 (with Dan Jurgens, Marvel Comics, 2000)

• 2006: Won "Best Painter/Multimedia Artist (Interior)" Eisner Award, for Hip Flask: Mystery City