Series one

The first series of six episodes ran from 22 February to 29 March 2011.^[2] The series followed a group of seven junior doctors at the Newcastle General Hospital and Royal Victoria Infirmary. On 13 October 2011, BBC Three aired a follow-up special, entitled Junior Doctors – One Year Check Up.^[3]

• Adam Beaini, age 24, F1 (Newcastle University)
• Katherine Conroy, age 24, F1 (Cambridge University)
• Lucy Holmes, age 24, F1 (Newcastle University)
• Jon Barclay, age 24, F2 (Newcastle University)
• Suzi Batchelor, age 24, F2 (Newcastle University)
• Andy Kong, age 25, F2 (Newcastle University)
• Keir Shiels, age 28, F2 (Cambridge University)

Series two

The second series consisted of seven episodes and ran from 24 January to 6 March 2012.^[4] The series followed a group of eight junior doctors at the Chelsea and Westminster Hospital. On 3 December 2012, BBC Three aired a follow-up special, entitled Junior Doctors – One Year Check Up.^[5]

• Sameer Bahal, age 25, F1 (Imperial College)
• Akira Fukutomi, age 25, F1 (Imperial College)
• Lucy Hollingworth, age 25, F1 (University of Manchester)
• Priya Mangat, age 25, F1 (King's College London School of Medicine)
• Milla Marinova, age 26, F1 (Barts and The London School of Medicine and Dentistry)
• Andy Steval, age 23, F1 (Newcastle University)
• Ben Allin, age 26, F2 (Imperial College)
• Amieth Yogarajah, age 27, F2 (Cambridge University)

Series three

The third series consisted of seven episodes and ran from 17 January to 28 February 2013.^[6] The series followed a group of seven junior doctors at the Royal Liverpool University Hospital. An eighth junior doctor, Carol Sondhi, 27, from Malawi was filmed for the series^[7] but did not feature in the opening episode.

• Edward Bennison, age 28, F1 (University of Ferrara, Italy)
• Tom Morris, age 25, F1 (University of Liverpool School of Medicine)
• Emily Phipps, age 25, F1 (University of Liverpool School of Medicine)
• Tristan Townsend, age 28, F1 (University of Liverpool School of Medicine)
• Jennifer Whiteley, age 25, F1 (University of Liverpool School of Medicine)
• Oliver Harris, age 25, F2 (University of Nottingham)
• Kiera Vaughan, age 25, F2 (University of Keele)

Series four

Series 4, renamed Junior Doctors: Blood, Sweat and Tears, began on 25 October with seven new doctors at Wolverhampton's New Cross Hospital.^{[citation needed]}

Series five

Series 5, renamed Junior Doctors: On the Front Line, began on 22 September 2019 with six new doctors at Salford Royal Hospital. ^{[citation needed]}

• Nicholas Ronan, age 28, F1
• Howra Ktayen, age 24, F1
• Sofia Arkhipkina, age 24, F1
• Zohaib Khawaja, age 25, F1
• Luke Mcevoy, age 26, F2
• Thomas Gubbin, age 26, F2

Spin-off

A spin-off named "Junior paramedics: Your life in their hands" was broadcast from February 2014 to April 2014. The show follows nine junior paramedics; Lucy Wright, Bryn Griffiths, Stephanie Cook, Lucy Mellor, Max Brufton, Amy Allen, Ashley Strawbridge, Victoria Hilditch, and Nick Bailey on a six-week placement with East Midlands Ambulance Service.^[8]