KKPX-TV (channel 65) is a television station licensed to San Jose, California, United States, serving as the Ion Television outlet for the San Francisco Bay Area. The station is owned and operated by the Ion Media subsidiary of the E. W. Scripps Company, and has offices on Price Avenue in Redwood City; its transmitter is located atop San Bruno Mountain.

The station first signed on the air on November 15, 1986, as KLXV-TV (the last three letters of the callsign representing the Roman numeral for 65) and was an affiliate of the Trinity Broadcasting Network. In 1995, the station became an affiliate of the infomercial service InTV. In January 1998, the station's call letters were changed to KKPX after Paxson Communications (now Ion Media) bought the station. KKPX became a charter owned-and-operated station of Pax TV (the predecessor of Ion Television, to which the network was renamed in 2007) on August 31.

From 2000 to 2005, KKPX, during weeknights, aired rebroadcasts of KNTV (channel 11)'s 6 and 11 p.m. newscasts at 7 and 11:30 p.m. instead of airing newscasts from then-NBC affiliate KRON-TV (channel 4). The newscasts were originally branded as NewsChannel 11 on Pax after KNTV switched its affiliation from ABC to The WB. When KNTV joined NBC in January 2002, the newscasts were first renamed to NBC 3 News on Pax, then to NBC 11 News on Pax several months later, after KNTV stopped branding by its common channel number on Bay Area cable systems. Like most other such arrangements involving Pax stations and major network affiliates, the simulcasts were dropped on June 30, 2005 (the day prior to Pax's rebranding as i: Independent Television).