1984–2000: Early career, NBC and Brillstein-Grey

Reilly began his career as a freelance production assistant in New York City where he worked on over 150 commercials and music videos. To pursue a career in television, he took a road trip to Los Angeles, initially earning a position as a publicist with Universal Pictures and later hired by Brandon Tartikoff as a manager of creative affairs at NBC in 1988.^[8][9][11]

In his early years at NBC he developed Saved by the Bell.^[12][13][14] He later supervised Law & Order in its first season and developed the pilot episode for ER while serving as vice president of drama development from 1992 to 1994.^{[15][16][17][18]}

In 1994, Reilly left his role at NBC to become president of television at Brillstein-Grey Entertainment.^[19][20] While there, Reilly was responsible for shepherding some of television's top shows, such as NBC's Just Shoot Me and NewsRadio, and The WB's The Steve Harvey Show, and the pilot for HBO's The Sopranos.^[18][21] He resigned from the position in 2000.^[6][19]

2000–2003: Move to FX

In 2000, Reilly joined FX as president of entertainment.^[6] While at FX, he helped the new network become a profitable, creative business. While there he also transitioned the network's programming from syndicated reruns to original programming including The Shield, Nip/Tuck, and Rescue Me.^[17][22][23] Within a year of his arrival, FX made cable history with its seminal series, The Shield broke cable ratings records when it premiered and received both a Golden Globe Award for Best Drama Series and an Emmy Award for lead actor Michael Chiklis in 2002.^[11][24][25] Reilly also championed Lucky, the first television project from the Cullen brothers.

2003–2007: Second stint at NBC

In June 2003, Reilly was named the president of primetime development at NBC.^[17] In May 2004, he was promoted to president of the network's entire entertainment division, which included primetime, daytime, and late night programming.^[24] Reilly's second tenure at the network was marked by volatility largely due to the fact that major properties like The West Wing, Friends, Frasier, and Will & Grace came to a conclusion.^[11][26]

Despite NBC's poor performance, Reilly oversaw the development of some of the network's more prominent shows that helped to define the network in that decade. His vocal support of The Office helped it survive its low-rated first season. He also helped get My Name Is Earl on the air despite objections from other NBC Universal executives.^[27] Reilly has been credited with developing other shows such as Heroes,^[27] 30 Rock,^[28] Friday Night Lights,^[29] Deal or No Deal, America's Got Talent, and others.^[11][26]

Despite having received a new three-year contract at NBC in March 2007, Reilly's employment with NBC Universal was terminated in late May 2007, and he departed soon after.^[30][31][32] Under his administration, NBC's programs received 69 Emmy nominations that year, and a total of 235 nominations and 50 wins.^[28]

2007–2014: Return to Fox

Six weeks after leaving NBC,^[32] Reilly was hired as president of entertainment at Fox. The move reunited him with Peter Liguori whom he also worked with while at FX.^[33] Early in his tenure at Fox, Reilly developed and launched the J. J. Abrams thriller Fringe,^[13] and Seth MacFarlane's Family Guy spinoff, The Cleveland Show. He also was involved in the launch of Fox Inkubation, a joint venture with 20th Century Fox that provided funding to animators to create two-minute shorts that could eventually be developed into television pilots.^[34] Through the program, Justin Roiland first generated the concept for what would become the Adult Swim show Rick and Morty.

In 2009, he launched Glee which would go on to win the Golden Globe Award for Best Television Series – Musical or Comedy in 2010.^[35] Reilly is generally credited with creating Jane Lynch's character, Sue Sylvester, on the show.^[36][37] In 2011, Reilly also championed New Girl, the network's highest-rated fall sitcom debut in 10 years, and the singing competition show, The X Factor.^[38][39]

Reilly was promoted to chairman of entertainment for Fox in August 2012.^[40] He later introduced the shows Brooklyn Nine-Nine, Bob's Burgers, and The Mindy Project.^[41][42]

At Fox, Reilly oversaw the network's leadership and investment in digital and social media.^[43] He is credited as "the architect" behind the Animation Domination High-Def,^[44] an independent digital animation subsidiary generating alternative animation for digital channels and a late-night block on Fox.^[45]

Reilly also initiated a "no pilot season" strategy (designed to nurture fewer new Fox shows with more investment).^[46][47][48] Prior to his departure, he also greenlit shows, including Empire, Gotham,^[46] and The Last Man on Earth.^[49] During his time at Fox from 2007 to 2014, the network had a seven-year run as television's top-rated network for adults aged 18 to 49.^[41] He left Fox in May 2014.^[50]

2014–2020