Colorado Avalanche

On April 5, 2010, Shattenkirk was signed to an amateur try-out contract with the Avalanche's American Hockey League (AHL) affiliate, the Lake Erie Monsters, to conclude the 2009–10 season.^[11] On April 7, 2010, he made his professional debut, recording an assist and a shootout goal in a 5–4 victory over the Abbotsford Heat.^[12]

On November 4, 2010, Colorado recalled Shattenkirk from Lake Erie and made his NHL debut in a home game against the Vancouver Canucks that same day.^[13] Shattenkirk was one of 12 rookies selected to participate in the 2011 NHL All-Star festivities in Raleigh, North Carolina.^{[citation needed]}

St. Louis Blues

On February 19, 2011, in a swap of four former first-rounders, Shattenkirk, Chris Stewart and a conditional second-round pick were traded to the St. Louis Blues in exchange for Erik Johnson, Jay McClement and a conditional first-round pick.^[14] Later that day, Shattenkirk made his home debut with the Blues at the Scottrade Center, recording an assist in a decisive 9–3 victory over the Anaheim Ducks.^[15]

With the NHL lockout effectively delaying the start to the 2012–13 season, on November 26, 2012, Shattenkirk signed a lockout contract in Finland, joining Blues teammate Kris Russell with HC TPS of the SM-liiga.^[16] He played in 12 games before the labor dispute was solved, scoring two goals and six points for TPS.^{[citation needed]}

On June 26, 2013, Shattenkirk signed a four-year, $17 million extension with St. Louis.

Washington Capitals

In the final year of his contract, during the 2016–17 season, the Blues were unable to work out an extension with Shattenkirk as he approached free agency.^[17] On February 27, 2017, prior to the trade deadline, Shattenkirk was traded (alongside Pheonix Copley) to the Washington Capitals in exchange for Zach Sanford, Brad Malone, a 2017 first-round draft pick and a conditional second-round draft pick in 2019. Shattenkirk left the Blues having played in 425 games and collecting 258 points, placing fifth all-time amongst defensemen in franchise history.^[18]

New York Rangers

On July 1, 2017, Shattenkirk signed a four-year, $26.65 million contract with the New York Rangers.^[19] Shattenkirk had been connected to the Rangers via rumors for months leading up to his free agency, which further heated up following a June 23 trade in which New York traded away Derek Stepan, clearing up cap space.^[20][21] On January 19, 2018, it was announced Shattenkirk would have surgery to repair a torn meniscus in his left knee and that he would be out of the lineup indefinitely. It was later revealed he had torn the meniscus during training camp and had played through the first half of the season with it before opting for surgery.^[22] Even though he was initially expected to be able to return for the end of the regular season and for the 2018 Stanley Cup playoffs, the Rangers would fall out of playoff contention and eventually opted to shut down Shattenkirk for the season.^{[citation needed]}

On July 31, 2019, Shattenkirk's contract was bought out by the New York Rangers after a disappointing 2018–19 season when he registered just 2 goals and 28 points in 73 games.^[23]

Tampa Bay Lightning

Shattenkirk signed with the Tampa Bay Lightning on a one-year, $1.75 million deal for the 2019–20 season. As a member of the Lightning, Shattenkirk would win the Stanley Cup, recording 3 goals and 10 assists for 13 points in the playoffs.

Anaheim Ducks

On October 9, 2020, Shattenkirk left the Lightning as a free agent and was signed to a three-year, $11.7 million contract with the Anaheim Ducks.^[24]

Adding a veteran presence on the rebuilding Ducks blueline, Shattenkirk added 4 goals and 23 points through 75 games during the 2022–23 season, his final year under contract.

Boston Bruins

As a free agent from the Ducks, Shattenkirk was signed to a one-year, $1.05 million contract with the Boston Bruins on July 1, 2023.^[25]