The Confederation of African Football (CAF) is the governing body for association football in Africa. It organizes three club competitions: the CAF Champions League (formerly African Cup of Champions Clubs), the CAF Confederation Cup and the CAF Super Cup. CAF was also responsible for the African Cup Winners' Cup and the CAF Cup, until their merging in 2004 when Confederation Cup took their places.

This article does not cite any sources. (June 2022)

Egyptian side Al Ahly have won a record total of 25 titles in CAF competitions, nine more than his local rival Zamalek and eleven more than TP Mazembe.

Until the first Confederation Cup final in 2005, the only team to win every CAF club competition was Espérance Sportive de Tunis (Tunisia). They won their first African Champions Cup in 1994, their first Cup Winners' Cup in 1998 and their first CAF Cup in 1997; becoming also the first team to win the set composed by the three oldest continental trophies,^{[lower-alpha 1]} a feat subsequently equaled only by Algerian JS Kabylie in 2000 and Tunisian Étoile Sportive du Sahel in 2007. Additionally, ES Tunis won its first Super Cup in 1995 and its first Afro-Asian Club Championship Cup in the same year.

Egyptian clubs have won the most titles (42), ahead of clubs from Morocco (24) and Tunisia (24).

Club World Cup is not included in this list because it's a FIFA competition.

• CAF Champions League
• African Cup Winners' Cup
• CAF Cup
• CAF Confederation Cup
• CAF Super Cup
• Afro-Asian Club Championship

• CAF official website