In basketball, an assist is a pass to a teammate that directly leads to a score by field goal.^[1] All of the players on this list have recorded at least 20 assists in a National Collegiate Athletic Association (NCAA) Division I game. Assists were first recognized in the 1950–51 season, but only lasted through 1951–52 before the NCAA stopped recording them until the 1983–84 season.^[2] All players on this list have accumulated at least 20 assists in a game while playing for a Division I university. Through the most recent 2019–20 season, this has occurred only 22 times.^[2][3]

The single game record is 24 assists, set by Cameron Parker of Sacred Heart on December 1, 2019. The previous record of 22 had been accomplished by four players.^[3] Four 21-assist performances have been recorded, while the 15 remaining instances have been 20 assists.^[2][4]

No school has had more than one player reach the 20-assist mark. Southern University is on this list four times via Avery Johnson's four 20-assist games during his career. Johnson, who spent his first two college seasons at New Mexico Junior College and then Cameron University, only played NCAA Division I basketball for two seasons (1987, 1988). He led Division I in assists per game both years and set the still-standing record of 13.30 assists per game in 1987–88.^[2] Cameron Parker joins him as the only two players in Division I history to reach 20 assists more than once.

• List of National Basketball Association players with most assists in a game