Locicortolone

Locicortolone
Clinical data
Other names	Locicortone; RU-24476; 9α,11β-Dichloro-21-hydroxy-16α-methylpregna-1,4-diene-3,20-dione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name (8S,9R,10S,11S,13S,14S,16R,17S)-9,11-Dichloro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one;
CAS Number	65049-45-8;
PubChem CID	12905327;
ChemSpider	32698996;
UNII	9R09I46GBS;
CompTox Dashboard (EPA)	DTXSID70215366 ;
Chemical and physical data
Formula	C22H28Cl2O3
Molar mass	411.36 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)Cl)Cl)C;
	InChI InChI=1S/C22H28Cl2O3/c1-12-8-16-15-5-4-13-9-14(26)6-7-21(13,3)22(15,24)18(23)10-20(16,2)19(12)17(27)11-25/h6-7,9,12,15-16,18-19,25H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1; Key:FKRMBGXNTOTQDI-IIEHVVJPSA-N;

Locicortolone

Chemical compound

Locicortolone (developmental code name RU-24476), or locicortone, is a synthetic glucocorticoid corticosteroid which was never marketed.^[1]^[2]

Quick Facts Clinical data, Other names ...

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This article uses material from the Wikipedia article Locicortolone, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[NegwerScharnow2001-1] [1]
Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3795. ISBN 978-3-527-30247-5.

[WHO2013-2] [2]
"The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). World Health Organization. 2013. Archived from the original (PDF) on 22 October 2014.

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Locicortolone

References

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