Lucensomycin

Lucimycin

Lucimycin

Chemical compound

Lucimycin (INN, also known as lucensomycin and etruscomycin) is a macrolide antibiotic synthesized by the bacterium Streptomyces lucensis. It belongs to the group of polyene antimycotics and was first isolated in the 1960s. It has seen only limited clinical use.

Quick Facts Identifiers, Properties ...

Lucimycin is also produced by the Streptomyces cyanogenus S136, where the full biosynthetic gene cluster for the production of this compound was described.[1]

References

  1. [1]
    Yushchuk O, Ostash I, Mösker E, Vlasiuk I, Deneka M, Rückert C, et al. (February 2021). "Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA". Scientific Reports. 11 (1): 3507. Bibcode:2021NatSR..11.3507Y. doi:10.1038/s41598-021-82934-6. PMC 7875965. PMID 33568768.

Further reading


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