Matthew Norton Wise (born 1940) is an American historian of science who is an emeritus professor at the University of California, Los Angeles (UCLA). He was also the co-director of the UCLA Center for Society and Genetics.

Wise was born on April 2, 1940, in Tacoma, Washington. He earned a BSc in physics from Pacific Lutheran University in 1962 and went on to obtain two PhDs: a PhD in experimental nuclear physics from Washington State University in 1968, and a PhD in the history of science from Princeton University in 1977.

Wise was a physics professor at Auburn University and Oregon State University before becoming a history professor at UCLA and then, from 1991 to 2000, at Princeton, before returning to UCLA, where he remained until his retirement.

He famously attacked Gross and Levitt's book in which they perceive the obstruction of science by the academic left.^[1]

In 2004/5 he taught at Utrecht University and also spent much of his time at the Max Planck Institute in Berlin.

He is the recipient of the Berthold Leibinger Berlin Prize and was a Fellow at the American Academy in Berlin for Spring 2012.