MIR6087

MIR6087

MIR6087

MicroRNA

MicroRNA 6087 is a miRNA that in humans is encoded by the MIR6087 gene. [1]

Quick Facts Identifiers, Aliases ...

Function

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding.

The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products.

The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

References

  1. [1]
    "Entrez Gene: MicroRNA 6087". Retrieved 2016-11-16.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


Stub icon

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article MIR6087, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.