Manuel António Leitão da Silva (born 29 January 1946), known as Manuel António, is a Portuguese retired footballer who played as a striker.

He amassed Primeira Liga totals of 247 matches and 111 goals over 12 seasons, with Académica (two spells) and Porto.

Manuel António was born in Santo Tirso, Porto District. In a 14-year professional career, he played almost exclusively for two teams; having started out at Académica de Coimbra, his excellent performances earned him a transfer – at only 19 – to FC Porto, where he appeared sparingly over three years (still managing to score regularly).^[1]

In 1968, Manuel António returned to Académica, being crowned the Primeira Liga's top scorer in the first season in his second spell, with the Students finishing in sixth place.^[2] He all but saw out his career eight years later at the same club, still having a further four campaigns in double digits.

Manuel António won four caps for Portugal in eight months, his debut coming on 6 April 1969 in a 0–0 friendly draw against Mexico.^[3]

After retiring, Manuel António majored in medicine, being in charge of Coimbra's Portuguese Institute of Oncology for several years.^[1]