Manuel de la Cruz (1750–1792) was a Spanish painter. He was born and died in Madrid. He distinguished himself by his pictures in the cathedral of Carthagena and in the monastery of San Francisco el Grande at Madrid. In the Gallery of the latter city there is a painting by him of The Annual Fair at Madrid. He also etched a few plates of heads of strongly marked character.

•  This article incorporates text from a publication now in the public domain: Bryan, Michael (1886). "De la Cruz, Manuel". In Graves, Robert Edmund (ed.). Bryan's Dictionary of Painters and Engravers (A–K). Vol. I (3rd ed.). London: George Bell & Sons.

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