Princess Maria Henrietta of Naples and Sicily (Italian: Maria Enrichetta Carmela; 31 July 1787 – 10 September 1792) was a member of the House of Bourbon and a princess of the Kingdom of the Two Sicilies. She was a daughter of Ferdinand I of the Two Sicilies and his first wife, Maria Carolina of Austria.

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Maria Henrietta was born at the Palace of Caserta in Naples to Ferdinand, Duke of Calabria, the third son of Charles III of Spain, and to Archduchess Maria Carolina of Austria, daughter Maria Theresa of Austria and her husband, Francis I, Holy Roman Emperor. She was baptized with the name Maria Enrichetta Carmel.