Mark Spencer Brewer (October 22, 1837 – March 18, 1901) was an American lawyer and politician from the U.S. state of Michigan who served four terms over two different stints in Congress between 1877 and 1891.

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Mark S. Brewer
Member of the U.S. House of Representatives from Michigan's 6th district
In office March 4, 1887 – March 3, 1891
Preceded by	Edwin B. Winans
Succeeded by	Byron G. Stout
In office March 4, 1877 – March 3, 1881
Preceded by	George H. Durand
Succeeded by	Oliver L. Spaulding
Member of the Michigan Senate from the 20th district
In office January 1, 1873 – January 1, 1875
Preceded by	Homer G. Barber
Succeeded by	Charles V. Babcock
Personal details
Born	Mark Spencer Brewer (1837-10-22)October 22, 1837 Addison Township, Michigan
Died	March 18, 1901(1901-03-18) (aged 63) Washington, D.C.
Resting place	Oak Hill Cemetery
Political party	Republican
Profession	lawyer

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Brewer was born in Addison Township, Michigan, and attended the rural schools and Romeo and Oxford Academies. He studied law, was admitted to the bar in 1864 and commenced practice in Pontiac. He was city attorney of Pontiac in 1866 and 1867 and circuit court commissioner for Oakland County 1866-1869. He was a member of the Michigan State Senate from the 20th District 1873-1874.

Brewer was elected as a Republican to the United States House of Representatives from Michigan's 6th District for the 45th and 46th Congresses, serving from March 4, 1877, to March 3, 1881.

He was appointed consul general to Berlin on June 30, 1881, by U.S. President James A. Garfield and served from August 29, 1881, until June 7, 1885.

He was again elected to the U.S. House for the 50th and 51st Congresses, serving from March 4, 1887, to March 3, 1891. He declined to be a candidate for renomination in 1890 and resumed the practice of law in Pontiac.

He is interred in Oak Hill Cemetery, in Pontiac, Michigan.

• United States Congress. "Mark S. Brewer (id: B000811)". Biographical Directory of the United States Congress.
• The Political Graveyard