Matilda Johanna Clerk (2 March 1916 – 27 December 1984) was a medical pioneer and a science educator on the Gold Coast and later in Ghana as well as the second Ghanaian woman to become an orthodox medicine-trained physician.^[1][2] The first woman in Ghana and West Africa to attend graduate school and earn a postgraduate diploma, Clerk was also the first Ghanaian woman in any field to be awarded an academic merit scholarship for university education abroad.^[1][3] M. J. Clerk was the fourth West African woman to become a physician after Nigerians, Agnes Yewande Savage (1929), the first West African woman medical doctor and Elizabeth Abimbola Awoliyi (1938) in addition to Susan de Graft-Johnson, née Ofori-Atta (1947), Ghana's first woman physician.^{[1][4][5][6][7][8]} These pioneering physicians were all early advocates of maternal health, paediatric care and public health in the sub-region.^{[1][4][9][10]} For a long time after independence in 1957, Clerk and Ofori-Atta were the only two women doctors in Ghana.^[3] By breaking the glass ceiling in medicine and other institutional barriers to healthcare delivery, they were an inspiration to a generation of post-colonial Ghanaian and West African female doctors at a time the field was still a male monopoly and when the vast majority of women worldwide had very limited access to biomedicine and higher education.^[1][3] Pundits in the male-dominated medical community in that era described Matilda J. Clerk as "the beacon of emancipation of Ghanaian womanhood."^[3][11]

Matilda Johanna Clerk was born on 2 March 1916 in Larteh in the Akuapem Mountains, where her father, Nicholas Timothy Clerk (1862–1961) was stationed as a Basel missionary at the time.^[3][12] Her Basel-trained theologian father was the first Synod Clerk of the Presbyterian Church of the Gold Coast from 1918 to 1932.^[13][3] and a founding father of the all boys’ boarding high school, the Presbyterian Boys’ Secondary School, established in 1938.^[14][15] Her mother, Anna Alice Meyer (1873–1934) was of Ga-Danish heritage.^[12][13] Meyer was the cousin of Emmanuel Charles Quist (1880–1959), a barrister and judge who became the first African President of the Legislative Council from 1949 to 1951, Speaker of the National Assembly of the Gold Coast from 1951 to 1957 and Speaker of the National Assembly of Ghana from March 1957 to November 1957.^[16]

Her paternal grandfather, Alexander Worthy Clerk (1820–1906), a Jamaican Moravian missionary, arrived in the Danish Protectorate of Christiansborg (now the suburb of Osu) in Accra in 1843, as part of the original group of 24 West Indian missionaries who worked under the auspices of the Basel Evangelical Missionary Society of Basel, Switzerland.^{[13][17][18][19]} Alexander W. Clerk was a pioneer of the Presbyterian Church of Ghana and a leader in education in colonial Ghana, establishing a boarding middle school, the Salem School at Osu in 1843.^[20] Her paternal grandmother, Pauline Hesse (1831–1909) was from the Gold Coast, and was of Danish, German and Ga-Dangme ancestry.^[21] Her grandaunt was Regina Hesse (1832─1898), a pioneer educator and school principal who worked with the Basel Mission on the Gold Coast.^[21]

M. J. Clerk's older brothers were Carl Henry Clerk (1895–1982) and Theodore S. Clerk (1909–1965).^[22][23] She had six other siblings and belonged to the notable historical Clerk family of Accra, Ghana.^[23] Carl Clerk was an agricultural educationist, school administrator, editor, journalist and church minister^[24] who served as the fourth Synod Clerk of the Presbyterian Church of the Gold Coast between 1950 and 1954 and Editor of the Christian Messenger newspaper from 1960 to 1963.^[22][25] Theodore Clerk was the first Ghanaian architect who planned and developed the port city of Tema, while her older sister, Jane E. Clerk (1904–1999), a teacher, was a pioneer education administrator in colonial Ghana.^[26][27][28]

She had her primary and middle school education at Presbyterian schools at Adawso and Aburi respectively.^[3] At the Aburi all girls' middle boarding school Matilda Clerk attended until the end of 1931, the European missionary teachers dubbed her the "Dux of the School."^[3] M. J. Clerk matriculated at Achimota College in 1932.^[3] She received a Cadbury scholarship in 1934.^[3] At Achimota, she obtained a Second Division Teachers’ Preliminary Certificate (1935) and Cambridge Senior School Certificate with exemption from London Matriculation (1937).

Matilda Clerk was elected the Girls’ School Prefect in her senior year at Achimota.^[3] She was also a trained pianist and harpist; as a student, she excelled in sports.^[3] Among her interests were embroidery, art (painting) and gardening.^[3]

In 1942, Matilda Clerk became the first Ghanaian woman to complete the intermediate preliminary course in basic medical science, taking advanced courses in physics, chemistry, botany and zoology at Achimota.^[3][29] The British colonial government at that time effectively allowed only male students to participate in the programme.^[30] Thus, before the school permitted M. J. Clerk to enroll in the course in 1940, her father had to formally petition the then Governor of the Gold Coast, Arnold Wienholt Hodson for a special waiver.^[2][30] She was the only candidate, male or female, to pass the first preliminary medical baccalaureate examinations known as the 1st M.B., London, in 1942.^[3]

Based on her superior academic performance, she was awarded a rare medical scholarship by the colonial government to study medicine (MBChB) at the University of Edinburgh from 1944 to 1949.^[1][3] By winning the award, she became the first Ghanaian woman in the annals of history and in any field to secure a scholarship for higher education abroad.^[3] At Edinburgh, she was active in the Student Christian Movement and the International Club.^[3] The second Ghanaian woman and fifth West African woman (jointly with Annie Jiagge) to receive a university baccalaureate degree, M. J. Clerk was also the first woman in Ghana and West Africa to pursue postgraduate qualifications at a graduate school when she obtained a diploma in tropical medicine and hygiene (DTM&H) in 1950 from the London School of Hygiene and Tropical Medicine, a constituent college of the University of London; she returned to her homeland in January 1951.^{[1][2][3][31][32]}

Matilda Clerk died suddenly, aged 68, on 27 December 1984 at her home in Osu, Accra.^[3] Her funeral service was held at the Ebenezer Presbyterian Church, Osu; her remains were buried in the church's graveyard, the Basel Mission Cemetery, also in Osu, Accra.^[3] The Ghanaian physician, scholar, university administrator and public servant Emmanuel Evans-Anfom delivered the eulogy at her funeral.^[3][11]

• Timeline of women in science
• Women in medicine