Mel can be the abbreviated version of the given names Melike, Melvyn, Melvin, Amelia, Melfyn, Melanie, Melika, Melhem, Melina, Melinda, Melody, Melissa, Melita /Melitta, Melchior, Melindro or Melville. It is also a standalone name from the Gaelic Maol, meaning bald; this was used to refer to tonsured men to mean servant, as in "Maol-Iosa" - Servant of Jesus.

People with this name include:

• Mel Allen (1913–1996), American sportscaster
• Mel B (born 1975), English singer, former member of the Spice Girls
• Mel Blanc (1908–1989), American voice actor
• Mel Bleeker (1920–1996), American National Football League player
• Mel Brooks (born 1926), American comedy filmmaker, writer and actor
• Mel C (born 1974), English singer, former member of the Spice Girls
• Mel Carter (born 1939), American soul and pop singer
• Mel Gibson (born 1956), American film actor and director
• Mel Giedroyc (born 1968), British TV presenter and comedian
• Mel Gray (disambiguation), several people
• Mel Harris (born 1956), American actress
• Mel Jones (born 1972), Australian cricketer
• Mel Kaye, subject of The Story of Mel, about the archetypal "real programmer"
• Mel Knight (born 1944), Canadian politician
• Mel Lastman (1933–2021), Canadian businessman and politician
• Mel Lisboa (born 1982), Brazilian actress
• Mel Martin (born 1947), British actress
• Mel McDaniel (1942–2011), American country music singer-songwriter
• Mel Ott (1909–1958), American baseball player
• Mel Peachey (born 1980), British television host
• Mel Rosen (1928–2018), American track coach
• Mel Smith (1952–2013), British actor, writer and director
• Mel Street (1933–1978), American country music singer
• Mel Stuessy (1901–1980), American football player
• Mel Tiangco (born 1955), Filipino journalist, host, news caster
• Mel Tillis (1932–2017), American country music singer-songwriter
• Mel Tormé (1925–1999), American jazz singer, composer, arranger, and drummer
• Mel Whinnen (born 1942), former Australian rules footballer
• Mel White (born 1940), American clergyman and author
• Mel Winkler (1941–2020), American actor
• Saint Mel (died 488), early Irish missionary and founder of the diocese of Ardagh
• Mel Robbins (born 1968), American podcast host, author, and motivational speaker

• Mel Burton, a character on the soap opera Hollyoaks
• Mel Bush, the companion character for the Sixth and Seventh Doctor in the Doctor Who television series
• Mel Karnofsky, a character from the television sitcom Frasier
• Mel Owen, a character on the soap opera Eastenders
• Mel Sharples, owner and cook of Mel's Diner on the American sitcom Alice
• Mel, a Welsh terrier in the direct-to-video animated film Balto III: Wings of Change
• Mel Vera, one of the main characters of the 2018 television series Charmed
• Sideshow Mel, a character on the cartoon show The Simpsons
• Mel, the title character of the video game Portal Stories: Mel
• Mel, a pug in the computer-animated film The Secret Life of Pets
• Cousin Mel, the antagonist of Grandma Got Run Over by a Reindeer
• "Mel" Melathia, a character in the Filipino Webtoon series Mage & Demon Queen
• Mel, a character in the video game The Last of Us Part II
• Mel Medarda, one of the main characters in the 2021 animated series Arcane: League of Legends

Mel, the leader in minions

• Mel, a character on the TV series Jack's Big Music Show

• Mell, Japanese singer

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