Mesopotamia is the historical region between the Tigris and Euphrates rivers, largely corresponding with the territory of modern Iraq.

Look up Mesopotamia in Wiktionary, the free dictionary.

Mesopotamia may also refer to:

• Mesopotamia (EP), an EP by The B-52's; or the title track of that album
• "Mesopotamia", the first track from the album Cruel Melody by Black Light Burns
• "The Mesopotamians", the last track in the album The Else by They Might Be Giants

• Mesopotamian crow, a bird native to the region of Mesopotamia
• "Mesopotamia", the Japanese name for the 1991 video game Somer Assault

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