Mettle may refer to:
- Mettle, see bravery.
- Mettle (album), album by Hugo Largo 1989
- "Mettle", a single by Leila from Blood Looms and Blooms
- Icky Mettle, album by Archers of Loaf
- Mettle (comics), a Marvel Avengers character
- Mettle the Mule, the mascot of the New York Mets