Michael Edward Driscoll (February 9, 1851 – January 19, 1929) was an American lawyer and politician from New York.

Born in Syracuse, New York, Driscoll moved with his parents to the town of Camillus, Onondaga County, in 1852. He attended the district schools, Monro Collegiate Institute, in Elbridge, Onondaga County, and graduated from Williams College in 1877. Then he studied law, was admitted to the bar in 1879, and commenced practice in Syracuse, New York.

He was appointed one of five commissioners to draft a uniform charter for second-class cities in the State. He was appointed attorney for the State superintendent of insurance in 1905. He served as member of the Taft party that visited the Philippine Islands and Asian countries in 1905. He served as chairman of the Republican State Convention in 1906.

Driscoll was elected as a Republican to the Fifty-sixth and to the six succeeding Congresses, holding office from March 4, 1899, to March 3, 1913. He was Chairman of the Committee on Elections No. 3 (Fifty-eighth through Sixty-first Congresses).

He engaged in the practice of law, traveling, and lecturing on his travels.

He died in Syracuse, New York, January 19, 1929; and was buried at the Oakwood Cemetery there.

• United States Congress. "Michael E. Driscoll (id: D000502)". Biographical Directory of the United States Congress.