Midwest FurFest (MFF) is a furry convention that takes place in Rosemont, Illinois, usually on the second weekend after Thanksgiving.^[1] MFF is presented by Midwest Furry Fandom Inc, an Illinois Educational Not-For-Profit Corporation that exists primarily for the purpose of holding an annual convention to facilitate education in anthropomorphic literature and art. It also facilitates the donation of funds to non-profit institutions, mainly of which promote the well-being of humans and/or animals. The convention was first held in 2000 and has grown to draw 15,547 attendees in 2023. As of December 2023^[update], the 2023 event is the most attended convention in fandom history.

This section relies largely or entirely upon a single source. (December 2021)

Midwest FurFest started as a furry focused part of the now defunct DucKon, a Chicago-based science fiction convention.^[2] The furry portion of the original convention was started at DucKon 3 in 1994 and was headed up by Robert King. Interest grew each year, and it was estimated that by DucKon 8 (1999) between one-quarter and one-third of those attended present due to interest in the furry component of the convention.^[1]

Interest in furry specific activities grew to a size that it was no longer feasible to exist as a part of DucKon, and the convention was spun off in 2000, with the creation of Midwest Furry Fandom Inc., with the first MFF happening in November 2000.^[1] The convention has grown from 473 attendees in 2000 to 13,641 in 2022, making it the largest furry convention in the world by more than 3,900 attendees over the previous largest convention, Anthrocon.^[3] It has helped raise over US$900,000 for various charities.^[4][5]