Morona Santiago (Spanish pronunciation: [moˈɾona sanˈtjaɣo]) is a province in Ecuador. The province was established on February 24, 1954. The capital is Macas.

The provincial economy is industrially unexploited to its potential due to poor means of transportation. Its economy relies largely on the tourist sector of the rain forest. The Sangay National Park and the indigenous town of Shuara are some of its main attractions.^{[citation needed]}

Ethnic groups as of the Ecuadorian census of 2010:^[3]

• Indigenous 48.4%
• Mestizo 46.6%
• White 3.1%
• Afro-Ecuadorian 1.2%
• Montubio 0.2%
• Other 0.5%

The province is divided into 12 cantons. The following table lists each with its population at the 2001 census, its area in square kilometres (km²), and the name of the canton seat or capital.^[4]

Luzmila Abad was born here^[5] and is one of its representatives (in 2023) at Ecuador's National Assembly.^[6]

• Provinces of Ecuador
• Cantons of Ecuador