During the 2003 invasion of Iraq by a United States–led coalition, the U.S. Defense Intelligence Agency developed a set of playing cards to help troops identify the most-wanted members of President Saddam Hussein's government, mostly high-ranking members of the Iraqi Regional Branch of the Arab Socialist Ba'ath Party or members of the Revolutionary Command Council; among them were some of Hussein's family members. The cards were officially named the "personality identification playing cards". As of 2021, all but four of the 52 most wanted have either died or been captured, eleven of whom have been released.

Each card contains the wanted person's address and, if available, the job performed by that individual. The highest-ranking cards, starting with the aces and kings, were used for the people at the top of the most-wanted list. The ace of spades is Saddam Hussein, the aces of clubs and hearts are his sons Qusay and Uday respectively, and the ace of diamonds is Saddam's presidential secretary Abid Hamid Mahmud al-Tikriti. This strict correspondence to the order of the most-wanted list was not carried through the entire deck, but sometime later in 2003, the list itself was renumbered to conform (almost) to the deck of cards. The card backs feature camouflage reminiscent of that seen on the Desert Camouflage Uniform.

According to US Navy Lieutenant commander Jim Brooks, a spokesman for the Defense Intelligence Agency, such playing cards have been used as far back as the American Civil War and again in World War II—Army Air Corps decks printed with the silhouettes of German and Japanese fighter aircraft fetch hundreds of dollars today—and in the Korean War. Troops often play cards to pass the time, and seeing the names, faces and titles of the wanted Iraqis during their games will help soldiers and Marines in case they run into the wanted individuals in the field, Brooks said.^[1]

The list of "Most Wanted" was the result of a multi-intelligence agency collaboration which included the Defense Intelligence Agency, Central Command, and representatives from all US Service Branch Intelligence entities. The "Most Wanted" names were then assigned to their respective cards by five US Army soldiers, 2LT Hans Mumm, SSG Shawn Mahoney, SGT Andrei Salter, SGT Scott Boehmler, and SPC Joseph Barrios, who were assigned to the Defense Intelligence Agency.^[2] The pictures used on the cards came from a number of intelligence agencies, but most were derived from "open sources". The deck of cards was first announced publicly in Iraq on 11 April 2003, in a press conference by Army Brig. Gen. Vincent Brooks, deputy director of operations at U.S. Central Command. On that same evening Max Hodges, a Houston-based entrepreneur, found and downloaded a high-resolution artwork file for the deck from a Defense Department web server. Discovering the following day that the file had vanished from the military web server he became the first eBay seller to offer the artwork file, in PDF, which could be used to reproduce the deck.^[3] He quickly contracted Gemaco Playing Card Company to print 1,000 decks for about $4,000 and started selling both the decks, in advance of receiving them from the printer, on eBay, Amazon.com and his own web site. When some of his early auctions for a $4 deck of cards quickly rose to over $120,^[4] it did not take long for other eBayers to jump on the bandwagon and print or order decks of their own to sell. In just a few days hundreds of sellers materialized and the price dropped to just a few dollars per deck.

The Texas-based Liberty Playing Card Company received an order to manufacture the cards for the U.S. Embassy in Kuwait and by claiming to be "the authorized government contractor" quickly became another popular domestic supplier for the commercial market. The U.S. military inadvertently included in the jokers the trademarked Hoyle joker owned by the United States Playing Card Company of Cincinnati, Ohio.

• Hamas most wanted playing cards, similar cards made for Israel during Israel-Hamas war
• Archaeology awareness playing cards
• Desert Storm trading cards
• Manhunt (military)
• Mercenaries (video game) – used a similar playing card scheme for enemy leaders.