Multiple Maniacs is a 1970 independent American black comedy horror film^[4] composed, shot, edited, written, produced, and directed by John Waters, as his second feature film and first "talkie".^[5] It features several actors who were part of the Dreamland acting troupe for Waters' films, including Divine, Mary Vivian Pearce, David Lochary, Mink Stole, Edith Massey, George Figgs, and Cookie Mueller. The plot follows a traveling troupe of sideshow freaks who rob their unsuspecting audience members.

In 2016, American art house film distributor Janus Films and video distribution company The Criterion Collection undertook a new restoration of the film, with its preview for the restored print released June 17, 2016, at the Provincetown Film Festival, and its national exhibition began August 5, 2016.

Lady Divine is the owner and operator of The Cavalcade of Perversion, a free exhibit of various perversions and fetish acts and obscenities, such as the "Puke Eater". The show is free, but the various performers must persuade and even physically drag reluctant passers-by to attend.

As the finale to every show, Lady Divine appears and robs the patrons at gunpoint. This arrangement seems successful to Mr. David, Lady Divine's lover, but Lady Divine becomes bored with the routine and decides to murder the patrons rather than merely robbing them. After escaping the murder scene, she comes home to Cookie, her prostitute daughter, and her new boyfriend Steve, a member of the Weather Underground.

Lady Divine receives a call from Edith, proprietor of the local bar, who informs her that Mr. David had been at her bar with another woman (Mary Vivian Pearce). Lady Divine heads there to catch them, but is raped on the way by two glue-sniffers. Meanwhile, Mr. David and his new lover Bonnie, a woman who desperately wants to be part of the troupe, engage in sex acts at the home he shares with Lady Divine, during which Bonnie anally penetrates him with a dildo.

While Lady Divine contemplates her rape, the Infant of Prague appears and leads her to a church. Making her way uncertainly into the church, Lady Divine prays, but is then approached and seduced by a strange young woman named Mink. They have a sexual encounter in the church pew, with Mink inserting a rosary in Divine's rectum while describing the Stations of the Cross.

Now lesbian lovers, Lady Divine and Mink go to Edith's bar with the intent to kill Mr. David and his mistress, but they are too late: David and Bonnie, who have by this time decided that they have to kill Lady Divine to protect themselves, have left.

Mr. David returns to Cookie's house, intending to kill Divine, but instead he finds Cookie and fellow Cavalcade performer Ricky there. An argument ensues, and Bonnie accidentally kills Cookie. They tie up Ricky and hide Cookie's corpse just before Divine and Mink return. When Bonnie tries to shoot Lady Divine, Divine attacks and kills her with a knife. She then turns on Mr. David and eviscerates him as well, cannibalizing his internal organs, and becoming more frenzied. Ricky suddenly surprises Mink, who shoots him. In a fit of anger, Divine accuses Mink of betrayal and stabs her. Divine becomes even more crazed upon finding her daughter Cookie's body hidden behind the couch.

Exhausted from the ordeal, Lady Divine collapses on a couch and is subsequently raped by a giant lobster. In the aftermath (mumbling "You're a maniac now, Divine"), she destroys a car, then wanders Baltimore trying to kill anyone she can. The National Guard appear, surround Lady Divine on the street, and shoot her, to the tune of "America the Beautiful".

• Divine as Lady Divine
• David Lochary as Mr. David
• Mary Vivian Pearce as Bonnie
• Mink Stole as Mink / The Religious Whore
• Cookie Mueller as Cookie Divine
• Edith Massey as Edith the Barmaid / Virgin Mary
• Paul Swift as Steve
• George Figgs as Jesus Christ
• Michael Renner Jr. as The Infant of Prague
• Rick Morrow as Ricky

Multiple Maniacs had its world premiere at the First Unitarian Church in Baltimore on April 10, 1970.^[1] Waters later recalled that he toured the film throughout the United States, showing it at small arthouse theaters and other venues which often required a deposit to screen features.^[10] The film also showed internationally, with screenings in England in early 1971.^[11] In 2024, Waters recalled an incident where the Ontario Censor Board burnt a print of Multiple Maniacs that he sent for review.^[12]

As of August 18, 2016, Multiple Maniacs has grossed $33,036 in North America.^[3]

• List of American films of 1970