Mycinamicin_III_3''-O-methyltransferase

Mycinamicin III 3''-O-methyltransferase

Mycinamicin III 3''-O-methyltransferase

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Mycinamicin III 3''-O-methyltransferase (EC 2.1.1.237, MycF) is an enzyme with systematic name S-adenosyl-L-methionine:mycinamicin III 3''-O-methyltransferase.[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + mycinamicin III S-adenosyl-L-homocysteine + mycinamicin IV
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The enzyme is involved in the biosynthesis of mycinamicin macrolide antibiotics.

References

  1. [1]
    Li S, Anzai Y, Kinoshita K, Kato F, Sherman DH (May 2009). "Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics". ChemBioChem. 10 (8): 1297–301. doi:10.1002/cbic.200900088. PMC 2861363. PMID 19415708.
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