There are numerous men's and women's college lacrosse teams at schools that are members of the National Association of Intercollegiate Athletics (NAIA), which is an alternate varsity athletic organization to the National Collegiate Athletic Association (NCAA).
The Wolverine-Hoosier Athletic Conference (WHAC) was the first NAIA lacrosse conference to offer a championship for both men and women.
During the summer of 2015, the NAIA approved men's and women's lacrosse to move from emerging sport status to national invitational. This move allows NAIA varsity teams to compete within the NAIA rather than an outside organization. The first NAIA National Invitational Tournament (NIT) was held in May 2016 in Greenville, SC. Lacrosse is required to remain an invitational sport for a minimum of two years before applying for full championship status. As of fall 2019 both men's and women's lacrosse remained on invitational status. The 2018 and 2019 men's and women's championships were held in Grand Rapids, Michigan, on the Aquinas College campus.