Operation Xcellerator was an operation conducted by the U.S. Drug Enforcement Administration, with cooperation from Mexican and Canadian authorities, against Sinaloa Cartel drug traffickers. In February 2009, after a 21-month operation, it totalled 755 suspects arrested across California, Minnesota, and Maryland.

In addition to the arrests of alleged drug traffickers, US$59.1 million in cash, over 12,000 kg (26,000 lb) of cocaine, 16,000 lb (7,300 kg) of marijuana, 1,200 lb (540 kg) of methamphetamine, 8 kg (18 lb) of heroin, 1.3 million ecstasy pills, 149 vehicles, 3 aircraft, 3 maritime vessels and 169 weapons were seized.^[1]

A large-scale meth laboratory was also uncovered, as was an ecstasy lab capable of producing 12,000 pills per hour.^[2]