Oppenheim is a German and Ashkenazi Jewish surname. Notable people with the surname include:

• A. Leo Oppenheim (1904–1974), Assyriologist
• Alan V. Oppenheim (born 1937), professor of Electrical Engineering at MIT and author
• Alexander Oppenheim (1903–1997), British mathematician and university administrator
• Alfred Freiherr von Oppenheim (1934–2005), associate of Sal. Oppenheim bank
• Alfred Oppenheim (chemist) (1878–1943), German chemist and manufacturer
• Avrohom Chaim Oppenheim (1796?–1824?), Rabbi at Péczel, Hungary
• Berthold Oppenheim (1867–1942), Moravian rabbi
• David Ernst Oppenheim (1881–1943), Austrian educator
• David Oppenheim (clarinetist) (1922–2007), American clarinetist and classical music and television producer
• David Oppenheim (poker player), American professional poker player
• David Oppenheim (rabbi) (1664–1736), chief rabbi of Prague
• Dennis Oppenheim (1938–2011), American conceptual artist, performance artist, sculptor, and photographer
• E. Phillips Oppenheim (1866–1946), English novelist
• Franz Oppenheim (1852-1929), German chemist, entrepreneur and industrialist
• Heinrich Bernhard Oppenheim (1819–1880), German jurist, politician, and philosopher
• Hermann Oppenheim (1858–1919), German neurologist
• James Oppenheim (1882–1932), American poet, author, and editor
• Jeanette Oppenheim (born 1952), Danish lawyer and politician, MEP
• Jill Arlyn Oppenheim (born 1940), American actress better known as Jill St. John
• Joachim Oppenheim (1832–1891), rabbi and author
• Jonathan Oppenheim, British scientist
• Jonathan Oppenheim (film editor) (1951–2020), American film editor
• L. F. L. Oppenheim (1858–1919), German jurist
• Max von Oppenheim (1860–1946), German diplomat and archaeologist
• Meret Oppenheim (1913–1985), Swiss artist and lyricist
• Moritz Daniel Oppenheim (1800–1882), German painter
• Noah Oppenheim (born 1980), American writer, television producer, and President of NBC News
• Rob Oppenheim (born 1980), American professional golfer
• Sally Oppenheim (born 1930), shortened name for Sally Oppenheim-Barnes, Baroness Oppenheim-Barnes, former UK member of Parliament
• Salomon Oppenheim, Jr. (1772–1828), founder of the Sal. Oppenheim bank
• Samuel Oppenheim (1857–1928), Austrian astronomer

• Oppenheim family, prominent European banking family since the 18th century
• Oppenheimer, A similar surname also of German and Ashkenazi Jewish origin

This page lists people with the surname Oppenheim.
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