Orsini is a surname of Italian origin, originally derived from Latin ursinus ("bearlike") and originating as an epithet or sobriquet describing the name-bearer's purported strength. Notable people with the surname include the following:

• Aaron Paul Orsini, American researcher on the intersection of psychelics and neurodivergence
• Alessandro Orsini, Italian sociologist
• Angel Orsini, American wrestler and bodybuilder
• Felice Orsini (1819–1858), Italian revolutionary who attempted to assassinate Napoléon III
• Francesca Orsini, Italian scholar of South Asian literature
• Giambattista Orsini (d. 1503), Italian Catholic Cardinal instrumental in the 1492 Papal Conclave
• Marina Orsini (born 1967), Canadian actress
• Nicolás Orsini (born 1994), Argentine footballer
• Richard Orsini, 13th-century ruler in Italy and the Balkans
• Umberto Orsini (born 1934), Italian stage, television, and film actor
• Valentino Orsini (1927–2001), Italian film director

• Orsini family, Italian noble family, including:
  • Alessandro Orsini (cardinal) (1592–1626), cardinal
  • Clarice Orsini (1453–1488), wife of Lorenzo de' Medici, Lady Of Florence, mother of Pope Leo X
  • Fulvio Orsini (1529–1600), Italian historian
  • Giordano Orsini (died 1438) (died 1438), 15th-century Italian cardinal
  • Giordano Orsini (died 1173) (died 1173), Catholic prelate
  • Giorgio Orsini (1410–1475), architect and sculptor
  • Pope Nicholas III, born Giovanni Gaetano Orsini
  • Giovanni Gaetano Orsini (cardinal) (c.1285–1335), nephew of Pope Nicholas III
  • John II Orsini (died 1335), known as the Despot of Epirus
  • Latino Orsini (1411–1477), Catholic cardinal
  • Latino Malabranca Orsini (d. 1294), Catholic prelate
  • Matteo Orsini (d. 1340), Catholic prelate
  • Napoleone Orsini (1420–1480), condottiero and papal commander
  • Paolo Orsini (1369-1416), condottiero
  • Paolo Orsini (1450-1503), condottiero
  • Paolo Giordano I Orsini (1541–1585), first duke of Bracciano
  • Paolo Giordano II Orsini (1591–1656), nobleman
  • Pope Benedict XIII, born Pietro Francisco Orsini
  • Rinaldo Orsini (d. 1450), Lord of Piombino
  • Virginio Orsini (1434–1497), Lord of Bracciano

• All pages with titles containing Orsini
• Ursini (disambiguation)

This page lists people with the surname Orsini.
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