Penfield is a surname. Notable people with the name include:

• Add Penfield (Addison Pierce Penfield, 1918–2010), North Carolina sports radio broadcaster
• Daniel Penfield (1759–1840), founder of Penfield, New York
• Edward Penfield (1866–1925), American illustrator and poster artist
• Frederic Courtland Penfield (1855–1922), American diplomat
• Roderic C. Penfield (1864–1921), American publisher, printer, editor, journalist, theatre critic, businessman, playwright, and lyricist
• Samuel Penfield Taylor (1827—1886), American entrepreneur
• Smith Newell Penfield (1837–1920), American composer
• Thomas Penfield Jackson (1937–2013), US District Court Judge
• Wilder Penfield (1891–1976), Canadian neurosurgeon

This page lists people with the surname Penfield.
If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.