Phosphoglycerol_geranylgeranyltransferase

Phosphoglycerol geranylgeranyltransferase

Phosphoglycerol geranylgeranyltransferase

Enzyme

In enzymology, a phosphoglycerol geranylgeranyltransferase (EC 2.5.1.41) is an enzyme that catalyzes the chemical reaction

geranylgeranyl diphosphate + sn-glyceryl 1-phosphate diphosphate + sn-3-O-(geranylgeranyl)glyceryl 1-phosphate
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Thus, the two substrates of this enzyme are geranylgeranyl diphosphate and sn-glyceryl 1-phosphate, whereas its two products are diphosphate and sn-3-O-(geranylgeranyl)glyceryl 1-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase. Other names in common use include glycerol phosphate geranylgeranyltransferase, geranylgeranyl-transferase, and prenyltransferase.

References

    • Zhang DL, Daniels L, Poulter CD (1990). "Biosynthesis of archaebacterial membranes. Formation of isoprene ethers by a prenyl transfer reaction". J. Am. Chem. Soc. 112 (3): 1264–1265. doi:10.1021/ja00159a067.


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