Polypeptide_N-acetylgalactosaminyltransferase
Polypeptide N-acetylgalactosaminyltransferase
Class of enzymes
In enzymology, a polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.41) is an enzyme that catalyzes the chemical reaction
- UDP-N-acetyl-D-galactosamine + polypeptide UDP + N-acetyl-D-galactosaminyl-polypeptide
Thus, the two substrates of this enzyme are UDP-N-acetyl-D-galactosamine and polypeptide, whereas its two products are UDP and N-acetyl-D-galactosaminyl-polypeptide.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. This enzyme participates in o-glycan biosynthesis and glycan structures - biosynthesis 1. It has 2 cofactors: manganese, and calcium.