Popilius Pedo Apronianus (died 205) was a Roman senator, who was active during the reign of Septimius Severus. He was Roman consul in the year 191 with Marcus Valerius Bradua Mauricus as his colleague.^[1]

A member of the Patrician order, Apronianus has been identified as the grandson of Gaius Popilius Carus Pedo, suffect consul in 147.^[2]

Apronianus is known to have been proconsular governor of Asia. While proconsul he was murdered on specious grounds: according to Cassius Dio, Arponianus' nurse reported having a dream where he had been engarbed^{[check spelling]} as emperor, and it was believed Apronianus had practiced magic to achieve this.^[3] Paul Leunissen dates his tenure as proconsul to either 204/205 or 205/206.^[4] Ségolène Demougin suggests Apronianus' fatal end was connected with the fall from power of Gaius Fulvius Plautianus, who was executed on 22 January 205; since proconsuls assumed their posts in the summer months, this would date his tenure to 204/205, and mean the procurator Aelius Aglaus served as interim governor until a successor could arrive in the province.^[5]