60S ribosomal protein L39 is a protein that in humans is encoded by the RPL39 gene.^[5][6]

Quick Facts RPL39, Available structures ...

RPL39
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5AJ0, 3J92, 4UJC, 3J7P, 4UJE, 3J7Q, 3J7R, 4D67, 4UJD, 4V5Z, 4D5Y, 3J7O
Identifiers
Aliases	RPL39, L39, RPL39P42, RPL39_23_1806, ribosomal protein L39
External IDs	OMIM: 300899 MGI: 1914498 HomoloGene: 133571 GeneCards: RPL39
Gene location (Human) Chr. X chromosome (human)[1] Band Xq24 Start 119,786,504 bp[1] End 119,791,630 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X A3.3 Start 36,346,173 bp[2] End 36,349,055 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence endometrium skin of abdomen subcutaneous adipose tissue lymph node spleen right adrenal gland rectum right uterine tube vagina Top expressed in yolk sac ganglionic eminence lip esophagus uterus duodenum urinary bladder jejunum bone marrow neural tube More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA binding structural constituent of ribosome Cellular component ribosome cytosol intracellular anatomical structure extracellular space cytosolic large ribosomal subunit polysomal ribosome Biological process SRP-dependent cotranslational protein targeting to membrane innate immune response in mucosa viral transcription nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translational initiation protein biosynthesis rRNA processing antimicrobial humoral immune response mediated by antimicrobial peptide cytoplasmic translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6170 67248 Ensembl ENSG00000198918 ENSMUSG00000079641 UniProt P62891 P62892 RefSeq (mRNA) NM_001000 NM_026055 RefSeq (protein) NP_000991 NP_080331 Location (UCSC) Chr X: 119.79 – 119.79 Mb Chr X: 36.35 – 36.35 Mb PubMed search [3] [4]
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the S39E family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein is the smallest, and one of the most basic, proteins of the ribosome. This gene is co-transcribed with the U69 small nucleolar RNA gene, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[6]