40S ribosomal protein S4, X isoform is a protein that in humans is encoded by the RPS4X gene.^[3][4][5]

Quick Facts RPS4X, Available structures ...

RPS4X
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 3J7R, 3J7P
Identifiers
Aliases	RPS4X, CCG2, DXS306, RPS4, S4, SCAR, SCR10, ribosomal protein S4, X-linked, ribosomal protein S4 X-linked
External IDs	OMIM: 312760 HomoloGene: 90857 GeneCards: RPS4X
Gene location (Human) Chr. X chromosome (human)[1] Band Xq13.1 Start 72,255,679 bp[1] End 72,277,248 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium lactiferous duct tibia visceral pleura parietal pleura corpus epididymis vulva superficial temporal artery hair follicle caput epididymis n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function rRNA binding structural constituent of ribosome protein binding RNA binding Cellular component cytoplasm polysome cytosol ribosome membrane focal adhesion intracellular anatomical structure cytosolic small ribosomal subunit small ribosomal subunit cytoplasmic ribonucleoprotein granule extracellular exosome extracellular matrix nucleoplasm ribonucleoprotein complex synapse Biological process viral transcription positive regulation of translation SRP-dependent cotranslational protein targeting to membrane multicellular organism development positive regulation of cell population proliferation translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing protein biosynthesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6191 n/a Ensembl ENSG00000198034 n/a UniProt P62701 n/a RefSeq (mRNA) NM_001007 n/a RefSeq (protein) NP_000998 n/a Location (UCSC) Chr X: 72.26 – 72.28 Mb n/a PubMed search [2] n/a
Wikidata
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Ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[5]