40S ribosomal protein S9 is a protein that in humans is encoded by the RPS9 gene.^[5][6][7]

Quick Facts RPS9, Available structures ...

RPS9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0, 4KZY, 3J7R, 4D61, 4KZX, 4D5L, 5FLX, 4UJD, 3J7P, 4KZZ, 4UJE, 4UJC
Identifiers
Aliases	RPS9, S9, ribosomal protein S9
External IDs	OMIM: 603631 MGI: 1924096 HomoloGene: 68145 GeneCards: RPS9
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.42 Start 54,200,809 bp[1] End 54,249,003 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 A1 Start 3,706,992 bp[2] End 3,709,896 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte right uterine tube skin of abdomen canal of the cervix lymph node appendix gallbladder right lobe of thyroid gland ganglionic eminence prostate Top expressed in medial ganglionic eminence thymus maxillary prominence lip spleen abdominal wall skin of abdomen molar calvaria lymph node More reference expression data BioGPS More reference expression data
Gene ontology Molecular function rRNA binding structural constituent of ribosome translation regulator activity protein binding RNA binding Cellular component cytoplasm cytosol ribosome membrane focal adhesion intracellular anatomical structure nucleolus small ribosomal subunit extracellular exosome nucleus nucleoplasm cytosolic small ribosomal subunit synapse ribonucleoprotein complex Biological process positive regulation of translational fidelity viral transcription SRP-dependent cotranslational protein targeting to membrane positive regulation of cell population proliferation translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein biosynthesis rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6203 76846 Ensembl ENSG00000274646 ENSG00000277359 ENSG00000274950 ENSG00000274626 ENSG00000275323 ENSG00000278270 ENSG00000278081 ENSG00000274005 ENSG00000277079 ENSG00000170889 ENSMUSG00000006333 UniProt P46781 Q6ZWN5 RefSeq (mRNA) NM_001013 NM_001321701 NM_001321702 NM_001321704 NM_001321705 NM_001321706 NM_029767 RefSeq (protein) NP_001004 NP_001308630 NP_001308631 NP_001308633 NP_001308634 NP_001308635 NP_084043 Location (UCSC) Chr 19: 54.2 – 54.25 Mb Chr 7: 3.71 – 3.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Close

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.^[7]