RU-56187
RU-56187
Chemical compound
RU-56187 is a nonsteroidal antiandrogen which was never marketed.[1][2][3][4][5] It shows 92% of the affinity of testosterone for the androgen receptor and negligible affinity for other steroid hormone receptors.[1][2] The medication is a silent antagonist of the androgen receptor.[5] RU-56187 is 3- to 10-fold more potent as an antiandrogen than bicalutamide or nilutamide in animals.[1] Both RU-56187 and RU-58841 appear to be prodrugs of cyanonilutamide (RU-56279) in vivo in animals.[3]