STK17A

STK17A

STK17A

Protein-coding gene in the species Homo sapiens


Serine/threonine kinase 17a is a protein that in humans is encoded by the STK17A gene.[3]

Function

This gene is a member of the death-associated protein (DAP) kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity.[3]

In a recent study the gene (among others) shows a major role in centenarians longer lifespan.[4]


References

  1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. Garagnani P, Marquis J, Delledonne M, Pirazzini C, Marasco E, Kwiatkowska KM, et al. (May 2021). Tyler JK, Suh Y, Shuldiner AR (eds.). "Whole-genome sequencing analysis of semi-supercentenarians". eLife. 10: e57849. doi:10.7554/eLife.57849. PMC 8096429. PMID 33941312.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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