March 11 (Flight day 1, Launch)

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• Space Shuttle Endeavour launches for mission STS-123

Endeavour launched on time at 02:28:14 EDT (06:28:14 UTC) early into the night of March 11, 2008, from Launch Complex 39A at the Kennedy Space Center.

The Flash Evaporator System switched from its primary controller to the backup controller during launch, and instrumentation for a few left-side control thrusters was lost due to a card failure. These anomalies were not expected to affect the mission.^[9]

March 12 (Flight day 2)

The shuttle closed in on the space station. The crew used a 50 ft (15 m) laser-tipped boom to inspect its wings and nose for any sign of launch damage. The inspection has been standard procedure ever since the 2003 Columbia disaster. Flight director Mike Moses said a quick look at the images the astronauts beamed down to Earth revealed no signs of trouble.

In addition to performing the inspection, the astronauts also prepared their spacesuits for the five planned spacewalks and gathered the tools they would need for the docking.^[10]

March 13 (Flight day 3)

Endeavour's commander, Dominic Gorie, guided the shuttle through a 360-degree backflip, known as the rendezvous pitch maneuver, to allow for full photographic surveillance of the thermal tiles on the Space Shuttle's underside before docking with the space station.^[11] Docking occurred at 03:49 UTC and the hatches between the two spacecraft were opened at 05:36 UTC on.^[12] After docking the pallet carrying Dextre was moved to the Payload ORU Accommodation (POA) of the Mobile Base Station (MBS) by Canadarm2.

March 14 (Flight day 4)

Spacewalkers Richard Linnehan and Garrett Reisman worked on installing Dextre. However, the Spacelab pallet carrying the SPDM would not power up.^[13] Engineers on the ground tried a software patch, though later suspected a design flaw in Dextre's temporary power cable caused the issue.^[14]

Crew members on board Endeavour used a robotic arm to remove the Japanese Logistics Module – Pressurized Section (JLP) from Endeavour's cargo bay and attach it to the space station. The JLP was attached to its interim location on the Harmony module at 08:06 UTC.^[15]

March 15 (Flight day 5)

The crew spent time outfitting the Japanese Logistics Module, transferring supplies and equipment into it from Space Shuttle Endeavour. The station's arm operators grappled the Canadian-built Dextre Friday at 01:59 UTC. Canadarm2 successfully powered up Dextre 11 minutes later. Mission Specialists Rick Linnehan and Mike Foreman spent the night in the station's Quest Airlock in preparation for the second spacewalk of the mission.^[16]

March 16 (Flight day 6)

Dextre was put together today during the second spacewalk of STS-123. Mission Specialists Richard Linnehan and Mike Foreman completed their 7-hour, 8-minute orbital stroll Sunday at 06:57 UTC. The spacewalkers encountered some difficulty removing two bolts that secured the robot arm during transport, and had to resort to using a prybar to remove them.

Throughout the day, the station and shuttle crew members continued outfitting the Japanese Logistics Module – Pressurized Section.^[17]

March 17 (Flight day 7)

The crews continued outfitting the Japanese Logistics Module – Pressurized Section, transferring supplies and equipment into it from Endeavour, as well as configuring racks inside the module. The crews tested the brakes in the robotic system's arms. One of the joints in the arm seemed to be operating right on the required margin. Engineers expressed confidence that this issue would be resolved

Rick Linnehan and Robert Behnken ended their day by "camping out" in the station's Quest Airlock.^[18]

March 18 (Flight day 8)

Linnehan and Behnken began the third EVA at 22:51 UTC. The excursion lasted six hours and 53 minutes. Linnehan and Behnken installed a spare parts platform, cameras, and tool handling assembly for Dextre. Among other tasks, they also checked out and calibrated Dextre's end effector and attached critical spare parts to an External Stowage Platform.

They were unable to attach a materials science experiment to the Columbus module due to issues with the attachment fitting, but anticipated another opportunity later in the mission.^[19]

March 19 (Flight day 9)

In a day highlighted by robotics activity, Dextre was attached to a power and data grapple fixture located on the U.S. laboratory Destiny. Canadarm2 grabbed the pallet that secured Dextre during its journey to the orbital outpost and returned the pallet to Space Shuttle Endeavour's payload bay for the trip back to Earth.

The station and shuttle crews also prepared hardware to be used in a shuttle tile repair test on the next spacewalk, and got some much needed off duty time.^[20]

March 20 (Flight day 10)

The crews of Space Shuttle Endeavour and the International Space Station got some off-duty time at the beginning of their 10th day in orbit. They also spoke to Japanese Prime Minister Yasuo Fukuda and participated in interviews with U.S. media.

The astronauts spent the remainder of their day configuring tools for the fourth STS-123 spacewalk and reviewing spacewalk procedures. Before going to sleep, Mission Specialists Robert L. Behnken and Mike Foreman entered the station's Quest airlock for the standard "camp out".^[21]

March 21 (Flight day 11)

Mission Specialists Robert L. Behnken and Mike Foreman completed the fourth STS-123 spacewalk at 04:28 UTC, spending six hours and 24 minutes on the excursion. The two shuttle crew members replaced a failed Remote Power Control Module — essentially a circuit breaker — on the station's truss. However, there were difficulties removing a power connector from the Z1 truss.

With Mission Specialist Rick Linnehan coordinating their activities from inside the orbiting complex, the spacewalkers also tested a repair method for damaged heat resistant tiles on the Space Shuttle. This technique used a caulk-gun-like tool named the Tile Repair Ablator Dispenser to dispense a material called Shuttle Tile Ablator-54 into purposely damaged heat shield tiles. The sample tiles will be returned to Earth to undergo extensive testing on the ground.^[22]

March 22 (Flight day 12)

The STS-123 crew performed the final inspection of Space Shuttle Endeavour's heat shield using the shuttle's robot arm and the Orbiter Boom Sensor System (OBSS). Gorie, Johnson, and Doi surveyed the orbiter's wings and nose cap to ensure that no damage had occurred to the tiles that protect Endeavour from the heat of reentry.

The crews spent the remainder of their day configuring tools and reviewing procedures for the flight's final spacewalk. This included the standard "camp out" in the station's Quest airlock for Behnken and Foreman.^[23]

March 23 (Flight day 13)

Michael Foreman and Robert Behnken completed their six-hour EVA at 02:36 (UTC), attaching a 50 ft (15 m) inspection pole to the International Space Station and completing other chores. Foreman and Behnken hooked an extra-long power cord to the inspection pole, to keep its lasers and cameras warm for the next two months, then secured the boom to the outside of the space station.

After finishing that task, Foreman inspected a jammed rotating joint that has restricted the use of a set of solar wings for months. NASA hopes to have a plan for dealing with the jammed joint by the end of the month, space station flight director Dana Weigel said.^[24]

March 24 (Flight day 14)

The crews of Space Shuttle Endeavour and the International Space Station completed their last full day together.

Much of the astronauts' morning was off-duty time. Afterward, the crews wrapped up transfers of equipment and supplies between Endeavour and the station, and out the tools needed for undocking and subsequent activities.

The STS-123 and Expedition 16 crews also held a joint crew news conference, answering questions from members of the media on Earth.^[25]

March 25 (Flight day 15)

The hatches between Endeavour and the International Space Station closed around 21:49 UTC, ending a 12-day stay at the ISS, with a scheduled undocking of 23:57 UTC. Because of problems with a command sent to solar arrays in the ISS, the undocking was delayed 28 minutes and occurred at 00:25 UTC.

March 26 (Flight day 16)

The crew of Space Shuttle Endeavour spent Tuesday getting ready for its journey home and the end of the STS-123 mission. Early in their day, the crew members performed a test of the thrusters that will be used to position the orbiter for re-entry and the control surfaces for its flight through the atmosphere.

The STS-123 astronauts also set up the recumbent seat for Mission Specialist Léopold Eyharts, who joined the crew of Endeavour on the International Space Station. The recumbent seat is a special seat designed to reduce the stress of gravity on those who have spent long periods of time in the weightless environment of space.^[26]

March 27 (Flight day 17, landing)

Flight controllers gave a no-go on de-orbit for the first landing opportunity at 23:05 UTC (19:05 EDT), due to unfavorable weather conditions at the Shuttle Landing Facility at Kennedy Space Center.^[27]

Weather conditions were acceptable for the second landing opportunity, planned for 00:39 UTC March 27, 2008 (20:39 EDT March 26, 2008). The landing occurred at the Shuttle Landing Facility, and was the sixteenth night landing of the Space Shuttle at KSC, 22nd Shuttle night landing overall. Coincidentally, this mission also began with a night launch.

The second landing opportunity was a complete success with main gear touchdown occurring at 20:39:08 EDT (00:39:08 UTC March 27, 2008), nose gear touchdown at 20:39:17 EDT (00:39:17 UTC March 27, 2008), and wheels stop at 20:40:41 EDT (00:40:41 UTC March 27, 2008), completing the STS-123 crew's 16 days, 14 hours, 12 minutes, 27 seconds space voyage.

The exhaust produced by the Hydrazine Gas Generator APUs on either side of Endeavour's tail fin created concern among some observers that something was amiss, as it appeared more pronounced than usual in NASA's visual light cameras.^[28] However, this exhaust is normal and expected. The three Hydrazine Gas Generator APUs are activated five minutes before the deorbit burn and are running for five minutes after wheels stop. The mono-propellant hydrazine changes phase due to a catalyst and reaches 1,700 °F (927 °C).^[29] The hydraulic power is needed for the shuttle's rudder/speed brake, elevons, body flap and landing gear during descent, and for the main engine nozzles' gimballing during ascent. Each of the Solid Rocket Boosters have two similar Hydrazine Gas Generators for their nozzle gimballing.