Saint-Sébastien is a municipality in Le Granit Regional County Municipality in the Estrie region of Quebec, Canada. It is named after Saint Sebastian, who died c. 288.

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Saint-Sébastien
Municipality
Location within Le Granit RCM
Saint-Sébastien Location in southern Quebec
Coordinates: 45°47′N 70°58′W[1]
Country	Canada
Province	Quebec
Region	Estrie
RCM	Le Granit
Constituted	March 15, 1975
Government [2]
• Mayor	France Bisson
• Federal riding	Mégantic—L'Érable
• Prov. riding	Mégantic
Area [2][3]
• Total	91.10 km2 (35.17 sq mi)
• Land	91.95 km2 (35.50 sq mi)
	There is an apparent contradiction between two authoritative sources
Population  (2021)[3]
• Total	674
• Density	7.3/km2 (19/sq mi)
• Pop 2016-2021	2.6%
• Dwellings	329
Time zone	UTC−5 (EST)
• Summer (DST)	UTC−4 (EDT)
Postal code(s)	G0Y 1M0
Area code	819
Highways	R-263
Website	www.st-sebastien.com

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In the 2021 Census of Population conducted by Statistics Canada, Saint-Sébastien had a population of 674 living in 301 of its 329 total private dwellings, a change of 2.6% from its 2016 population of 657. With a land area of 91.95 km² (35.50 sq mi), it had a population density of 7.3/km² (19.0/sq mi) in 2021.^[4]