Saint Gudula was born in the pagus of Brabant (in present-day Belgium). According to her 11th-century biography (Vita Gudilae), written by a monk of the abbey of Hautmont between 1048 and 1051, she was the daughter of a duke of Lotharingia called Witger and Amalberga of Maubeuge. She died between 680 and 714.

Her name is connected to several places:

• Moorsel (where she lived)
• Brussels (where a chapter in her honour was founded in 1047)
• Eibingen (where the relic of her skull is conserved).

In Brabant she is usually called Goedele or Goule; (Latin: Gudila, later Gudula, Dutch: Sinte Goedele, French: Sainte Gudule).

The mother of Gudula, Saint Amalberga, embraced the religious life in the abbey of Maubeuge. She received the veil from the hands of St. Aubert, Bishop of Cambrai (d. about 668). Gudula had two sisters, St. Pharaildis and St. Reineldis, and two brothers, Saint Emebertus^[1] and Ermelinde.

Gudula was educated in the abbey of Nivelles by her godmother, Gertrude of Nivelles. When Gertrude died, Gudula moved back to her home at Moorsel, spending her time in good works and religious devotion. She was profuse in her alms for the poor,^[2] and frequently visited the church of Moorsel, situated about two miles from her parents' house.^[1] Nothing particular is recorded of Gudula beyond the singular holiness of her life.^[3]

Gudula died and was buried at Hamme (East Flanders). Later her relics were removed to the church of St. Salvator in Moorsel, where the body was interred behind the altar. During the reign of Charles, Duke of Lower Lorraine (977–992), the body of the saint was transferred to Saint Gaugericus' chapel in Brussels.^[1] Lambert II, Count of Leuven, (d. 1054) founded a chapter in 1047 in honour of Saint Gudula. Bishop Gerardus I of Cambrai (d. 1051) led the translation of her relics to the church of Saint Michael in Brussels. The church later became the famous Cathedral of St. Michael and St. Gudula.^[4] Her vita was written by Hubert of Brabant in the eleventh century.^[2]

On 6 June 1579, the collegiate church was pillaged and wrecked by the Protestant Geuzen ("Beggars"), and the relics of the saint were disinterred and scattered.

• Along with St. Michael, Gudula is a patron saint of Brussels.^[4]
• The feast of Saint Gudula is generally celebrated on 8 January (the day she died according her hagiography).^[5] However, in the diocese of Ghent (where Moorsel is situated) her feast is held on 19 January.
• Charlemagne made donations to the convent of Moorsel in her honour.

• The flower called tremella deliquescens, which bears fruit in the beginning of January, is known as Sinte Goedele's lampken (St. Gudula's lantern).
• The woodcarvers who produced statues of the saints born in the Holy Roman Empire, often depicted St. Gudula with a taper in her hand, but this originates probably out of confusion with the Paris Saint Geneveva tradition.
• The skull of St. Gudula is conserved in the Catholic Church of St. Hildegard in Eibingen, Germany.

• Saint Gudula, patron saint archive