San Domingo is one of the former names of Hispaniola.

San Domingo may also refer to:

• San Domingo (film), a 1970 West German drama film
• Santo Domingo Rebellion, a title sometimes used to refer to the Haitian Revolution (1791–1804)
• San Domingo School, a historic school building located in Maryland, USA
• San Domingo or Ruins of San Domingo, a settlements of the Portuguese in Gambia, West Africa; see History of the Gambia
• Fort San Domingo, a former Spanish fort in Taipei County, Taiwan, today the Tamsui District
• HMS San Domingo, a 74-gun warship launched in 1809 and sold in 1816
• HMS San Domingo, a planned Battle-class destroyer laid down in 1944 and then cancelled in 1945

• Domingo (name), a surname and given name
• Il furioso all'isola di San Domingo
• Saint Dominic, patron saint in which name is derived
• Santo Domingo (disambiguation)
• São Domingos (disambiguation)
• Domingo (disambiguation)

This disambiguation page lists articles associated with the title San Domingo.
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