The Secretary for Social Affairs and Culture (Chinese: 社會文化司; Portuguese: Secretariado para os Assuntos Sociais e Cultura) is a department of the Macao Government. The Secretariat is responsible for the education, health, tourism, social affairs and culture issues in the region.

The current department took over the role formerly held by the:

• Secretary for Social Affairs and Budget (Portuguese: Secretariado para os Assuntos Sociais e Orçamento)
• Secretary for Communications, Tourism and Culture (Portuguese: Secretariado para as Comunicações, Turismo e Cultura)

• Office of the Secretary for Social Affairs and Culture
• Education and Youth Development Bureau
• Cultural Affairs Bureau
• Sports Bureau
• Health Bureau
• Pharmaceutical Administration Bureau
• Social Security Fund
• Cultural Development Fund
• University of Macau
• Macao Polytechnic University
• Macao University of Tourism

Other principal officials of Macau:

• Secretary for Administration and Justice
• Secretary for Economy and Finance
• Secretary for Security
• Secretary for Transport and Public Works