Sep. 20 - Eastern Orthodox liturgical calendar - Sep. 22

All fixed commemorations below celebrated on October 4 by Orthodox Churches on the Old Calendar.^{[note 1]}

For September 21st, Orthodox Churches on the Old Calendar commemorate the Saints listed on September 8.

• Apodosis of the Exaltation of the Cross.^[1][2][3]

• Prophet Jonah (8th century BC)^{[2][4][5][note 2]} (see also: September 22 )
• Apostle Quadratus of the Seventy, Apologist (c. 130)^[1][2][7][8]
• Martyr Eusebius of Phoenicia (2nd century)^{[1][2][9][note 3]}
• Holy Six Martyrs, by the sword (298)^[5][10]
• Martyr Priscus of Phrygia.^[1][2][11]
• Martyrs Eusebius, Nestabus, Zeno, brothers, with Nestor and Busiris, of Gaza (360-363)^[1][2][12]
• Martyr Bassa of Tyre.^{[2][5][13][note 4]}
• Hieromartyr Hypatius, Bishop of Ephesus, and his Presbyter Andrew (730)^[1][14][15] (see also: September 20)
• Venerable Jonah the Sabbaite, the Presbiter (9th century), father of Sts. Theophanes the Hymnographer and Theodore Graptus^{[1][2][14][16][17]} (see also: September 22 )
• Venerables Isaacius (Akakios)^[18] and Meletius, Bishops of Sitis (Σίτης) in Cyprus.^{[1][2][14][note 5]}

• Saint Alexander, a bishop in the neighbourhood of Rome (2nd century)^{[19][note 6][note 7]}
• Saint Pamphilus, a martyr in Rome.^[6][19]
• Saint Mabyn (Mabena), a Cornish saint (6th century)^{[19][note 8]}
• Saint Gerulfus (Gerulph), a saint of Flanders (c. 746)^{[19][note 9]}
• Saint Maura, a holy virgin in Troyes, she reposed at the age of twenty-three after a life of prayer and good works (850)^[19]

• Venerable Daniel, founder of Shuzhgorsk Monastery, Belozersk (16th century)^[1][14][20]
• Saint Joseph, founder of Zaonikiev Monastery, Vologda (1612)^{[1][14][21][note 10]}

• Uncovering of the relics (1752) of St. Demetrius, Metropolitan of Rostov (1709)^{[1][2][5][25][38][39]}
• Repose of Arseny (Chagovstsov), Archbishop of Winnipeg (1945)^{[40][note 14]}
• Repose of Priest Dumitru Staniloae of Romania (1993)^[1]
• Synaxis of the Saints of Uglich.^[1][14]
• Synaxis of the Church of "Panagia Giatrissa" ("The Healer"), on Therasia in the Greek Cyclades (1950s)^[5]

• Prophet Jonah.
• Apostle Quadratus of the Seventy.
• Martyr Priscus of Phrygia.
• Venerables Isaac and Meletius of Cyprus.
• New Hieromartyr Platon (Aivazidis) of Amasya.
• St. Demetrius of Rostov.
• Abp. Arseny (Chagovstsov) of Winnipeg.
• Priest Dumitru Staniloae.