Seyssel (French pronunciation: [sɛsɛl]; Arpitan: Sèssél) is a commune in the Haute-Savoie department in the Auvergne-Rhône-Alpes region in south-eastern France.

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Seyssel
Commune
The village seen from the West
Coat of arms
Location of Seyssel
Seyssel Show map of France Seyssel Show map of Auvergne-Rhône-Alpes
Coordinates: 45°57′35″N 5°50′14″E
Country	France
Region	Auvergne-Rhône-Alpes
Department	Haute-Savoie
Arrondissement	Saint-Julien-en-Genevois
Canton	Saint-Julien-en-Genevois
Intercommunality	CC Usses et Rhône
Government
• Mayor (2020–2026)	Gérard Lambert[1]
Area 1	16.86 km2 (6.51 sq mi)
Population  (2021)[2]	2,342
• Density	140/km2 (360/sq mi)
Time zone	UTC+01:00 (CET)
• Summer (DST)	UTC+02:00 (CEST)
INSEE/Postal code	74269 /74910
Elevation	250–937 m (820–3,074 ft) (avg. 265 m or 869 ft)
1 French Land Register data, which excludes lakes, ponds, glaciers > 1 km2 (0.386 sq mi or 247 acres) and river estuaries.

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The part of the town across the Rhône is also named Seyssel but located on the western bank of the Rhône in the Ain department. It is a rare case in France of two homonymous communes adjacent to each other, similar to the situation of the village of Saint-Santin, divided between the communes of Saint-Santin (Aveyron) and Saint-Santin-de-Maurs (Cantal).

The Fier forms most of the commune's southern border, then flows into the Rhône, which forms the commune's western border.

• Communes of the Haute-Savoie department
• List of medieval bridges in France