The Shire of Wyndham East Kimberley is one of the four local government areas in the Kimberley region of northern Western Australia, covering an area of 117,514 square kilometres (45,372 sq mi) at Western Australia's northeastern corner. The Shire's seat of government was originally in Wyndham but now in the town of Kununurra, which is home to over half of the Shire's permanent population of around 7,000 (ABS 2016), while a council office is located at Wyndham.

El Questro Wilderness Park, Drysdale River National Park, Lake Argyle, the Argyle diamond mine and about half of Gibb River Road are located within the Shire's boundaries.

The East Kimberley Road District was gazetted on 10 February 1887. It was renamed as the Wyndham Road District on 4 September 1896. On 1 July 1961, it became the Shire of Wyndham–East Kimberley following the passage of the Local Government Act 1960, which reformed all remaining road districts into shires.^[3]

The early 1960s establishment of Kununurra and the Ord River Irrigation Area eventually led to moving the seat of local government from Wyndham to Kununurra, which by the 1980s had become a larger centre of population.

Many large cattle stations exist in the area including Argyle Downs which was established by Patrick Durack and his brother Michael in 1882.^[4]

The towns and localities of the Shire of Wyndham-East Kimberley with population and size figures based on the most recent Australian census:^[7][8]

• (* indicates locality is only partially located within this shire)

Indigenous communities in the Shire of Wyndham-East Kimberley:

• Dodnun community
• Kalumburu
• Kandiwal community
• Ngallagunda Community
• Pago Community
• Woolah (Doon Doon) Community

Protected areas within the Shire of Wyndham-East Kimberley:

National Parks

• Drysdale River
• Lawley River
• Mirima
• Mitchell River
• Prince Regent

Marine Parks

• North Lalang-garram Marine Park
• Lalang-garram / Camden Sound Marine Park
• Lalang-garram / Horizontal Falls Marine Park (Also covers areas in the Shire of Derby West Kimberley)

Nature Reserves & Conservation Parks

• Parry Lagoons Nature Reserve
• Pelican Island Nature Reserve
• Point Spring Nature Reserve
• Ord River Nature Reserve
• Barrbem Conservation Park
• Darram Conservation Park
• Goomig Conservation Park
• Jemarnde-wooningim Conservation Park
• Laterite Conservation Park
• Mijing Conservation Park
• Ngamoowalem Conservation Park

• Susan Bradley, former councillor and Shire president – Awarded an Order of Australia Medal for her contribution to the Kimberley community^[22][23]

As of 2023, 120 places are heritage-listed in the Shire of Wyndham–East Kimberley,^[24] of which three are on the State Register of Heritage Places.^[25]