Sisam is the Ottoman Turkish name for the island of Samos, Greece.

Sisam may also refer to:

• Ainu word for a Japanese person
• Sisam hypothesis on royal genealogies
• Syresham, UK village from which the English name Sisam is derived

• Charles Herschel Sisam (1879–1964), an American mathematician
• Kenneth Sisam (1887-1971), a New Zealand academic and publisher

This disambiguation page lists articles associated with the title Sisam.
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