Six Nations may refer to:

Look up Six Nations in Wiktionary, the free dictionary.

• Iroquois Confederacy, a group of First Nations/Native American peoples: Mohawk, Oneida, Onondaga, Cayuga, Seneca, and Tuscarora
  • Six Nations land cessions, in the late 17th and 18th centuries to British North America
  • Six Nations of the Grand River, First Nations reserve in Canada
    • Six Nations Polytechnic, third-level college in the reserve
• Celtic League, alliance of six "Celtic nations" (Ireland, Scotland, Wales, Brittany, Cornwall, Isle of Man)

• Six Nations Championship, an annual European rugby union competition involving England, Scotland, Wales, Ireland, France, and Italy
  • Six Nations Under 20s Championship, under-20 equivalent
  • Women's Six Nations Championship, women's equivalent
• Six Nations Tournament (ice hockey), a 1994–1996 European competition for clubs from Italy, Austria, France, Slovenia, Netherlands, and Denmark
• ICC Six Nations Challenge, a 2000–2004 cricket tournament for various teams below Test status.
• Nations Cup (netball), an annual tournament held in Singapore

• Six-party talks, international discussions with an aim to find a peaceful resolution to security concerns resulting from the North Korean nuclear weapons program

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