South Carolina Highway 41 (SC 41) is a 121.5-mile (195.5 km) state highway, connecting the Charleston region with eastern portions of the Pee Dee region in South Carolina. It serves as an alternative route to U.S. Route 52.

Quick Facts Route information, Length ...

South Carolina Highway 41
Route information
Maintained by SCDOT
Length	121.5 mi[1] (195.5 km)
Existed	1937–present
Major junctions
South end	US 17 in Mount Pleasant
Major intersections	US 17 Alt. in Jamestown US 521 near Andrews US 378 / SC 51 in Kingsburg US 501 in Ariel Crossroad US 76 / SC 917 in Mullins SC 9 in Lake View
North end	NC 41 at North Carolina state line
Location
Country	United States
State	South Carolina
Counties	Charleston, Berkeley, Georgetown, Williamsburg, Florence, Marion, Dillon
Highway system
South Carolina State Highway System Interstate US State Scenic
← SC 39 → SC 45

Close

The route travels generally in a south-north direction, beginning in Mount Pleasant and ending at the North Carolina state line just north of Lake View, where it continues as North Carolina Highway 41 towards Lumberton. The route is mostly rural, though it serves as an important arterial in suburban Mount Pleasant and passes through several small towns on its route northwards. It also provides several key river and swamp crossings in the Pee Dee region.

The current SC 41 was established in 1938 on a path from Lake View northeast to the North Carolina state line, where it replaced the original SC 94. The next year, a separate portion of the highway was established from the Marion–Dillon county line northward for about 5 miles (8.0 km). In 1940, the two segments were connected, and the highway was extended to what was then US 76 in Marion. Between 1944 and 1947, SC 41 was re-routed slightly within both Fork and Lake View. In 1949, its southern terminus was shifted to the northwest in Marion, to then end at what was then part of US 501 (now is US 501 Bus.). In September 1951, its path was re-routed in Fork to replace SC 57 to Centenary, SC 175 to Hemingway, and SC 511 to Mount Pleasant. Its former path from Centenary to Fork was redesignated as SC 41 Alt.^[2] In 1970, the highway was shifted off of the bypass around Andrews and was routed through the town. Approximately 25 years later, it was put back on the Andrews bypass; its former path was redesignated as SC 41 Bus.

The Wando River Bridge, a through truss swing bridge built in 1939, was replaced by 2020-2021. The new bridge will be four-lane with median (which can be used as a fifth lane during emergencies), and will be a fixed span bridge, tall enough for tall ships to pass. At a planned cost of $42.3 million, construction began in mid-2015.^[3][4][5]

• U.S. roads portal