Prior to its uniform adoption of proportional representation in 1999, the United Kingdom used first-past-the-post for the European elections in England, Scotland and Wales. The European Parliament constituencies used under that system were smaller than the later regional constituencies and only had one Member of the European Parliament each.

The constituency of South of Scotland was one of them.

1979–1984: Ayr, Ayrshire Central, Ayrshire South, Berwick and East Lothian, Dumfries, Galloway, Lanark, Roxburgh Selkirk and Peebles.

1984–1999: Ayr, Carrick Cumnock and Doon Valley, Clydesdale, Cunninghame South, Dumfries, East Lothian, Galloway and Upper Nithsdale, Roxburgh and Berwickshire, Tweeddale Ettrick and Lauderdale.